Name: Human LGR5 full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100073
Price: 8000.00 USD
Availability: InStock

Tag	C-Flag Tag
Target	LGR5
Synonyms	FEX; GPR49; GPR67; GRP49; HG38
Description	Human LGR5 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	O75473
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length LGR5 protein has a MW of 100.0 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Usage	Research use only
Conjugate	Unconjugated

Human LGR5 full length protein-synthetic nanodisc