Tag | C-Flag&Strep Tag |
---|---|
Target | |
Synonyms | BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
Description | Human LT4R1-Strep full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | Q15722 |
Expression Host | HEK293 |
Protein Families | GPCR,Transmembrane,Druggable Genome, |
Protein Pathways | GPCRDB Class A Rhodopsin-like,Nucleotide GPCRs,Cancer,Chemokines,Asthma,Autoimmune & Inflammatory Response,Chemokine and Receptor, |
Molecular Weight | The human full length LT4R1-Strep protein has a MW of 37.6 kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
Human LT4R1-Strep full length protein-synthetic nanodisc
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00
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