| Delivery | In Stock |
|---|---|
| Package | 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Molecular Weight | The human full length TSHR protein has a MW of 86.8 kDa |
| Target | |
| Formulation & Reconstitution | |
| Uniprot ID | P16473 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Autoimmune thyroid disease, Neuroactive ligand-receptor interaction |
| Synonyms | CHNG1; hTSHR-I; LGR3 |
| Expression Host | HEK293 |
| Description | Human TSHR full length protein-synthetic nanodisc |
| Background | The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. |
Human TSHR full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag TSHR-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody (Origene, TA592569) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TSHR-Nanodisc is 2.108ng/ml.
Figure2. Human TSHR-Nanodisc, Flag Tag on SDS-PAGE