Extracellular Domain Protein (ECD)

DIMA BIOTECH offers over 1000 ECD proteins covering more than 600 single pass membrane protein targets. All the proteins were made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target proteins. We also implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing tests, thermal stability tests, etc. 

Applications:

  • Immunogens for antibody drug development
  • Reagents used for CAR-T positive cell monitoring
  • Reagents for antibody screening and functional testing
  • Reagents for antibody affinity measurement
View All ECD Proteins

Hot Duggable Targets

Immune checkpoints are a class of proteins that regulate tumor immune microenvironment.

They can be classified into two categories, costimulatory immune checkpoints, such as OX40, GITR, ICOS, etc.; and co-suppressive immune checkpoints, such as PD1, CTLA-4, etc.

Right now there are a number of FDA approved drugs on co-suppressive targets, such as Yervoy, anti-CTLA-4 monoclonal antibody, Keytruda, anti-PD-1 monoclonal antibody and Tecentriq, anti-PD-L1 monoclonal antibody.

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DIMA Biotechnology LTD provide a full spectrum of functional proteins of new CAR T-cell targets.

All the proteins were made by using HEK293 mammalian cell secretion expression system and we implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing Tests, thermal stability tests, etc.

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In recent years, the biopharmaceutical market is growing rapidly.

Compared with small molecule drugs, antibody drugs exhibit higher specificity and selectivity.

Therefore, it showed tremendous progresses in the treatment of hematological cancers and autoimmune diseases.

Due to complex tumor immune microenvironment, the development of therapeutic antibody drugs for solid tumor is more challenging.

ECD Proteins

sp-pme101808 ptgfr sp1

ECD Proteins

Human PTGFR Protein, hFc Tag

SKU:  PME101808     Target:  PTGFR

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101807 ptger3 sp1

ECD Proteins

Human PTGER3 Protein, hFc Tag

SKU:  PME101807     Target:  PTGER3

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101806 prokr2 sp1

ECD Proteins

Human PROKR2 Protein, hFc Tag

SKU:  PME101806     Target:  PROKR2

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101805 ide sp1

ECD Proteins

Human IDE Protein, His Tag

SKU:  PME101805     Target:  IDE

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101804 lrrc4 sp1

ECD Proteins

Human LRRC4 Protein, His Tag

SKU:  PME101804     Target:  LRRC4

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101803 lilra5 sp1

ECD Proteins

Human LILRA5 Protein, His Tag

SKU:  PME101803     Target:  LILRA5

Price:10μg $72.00; 50μg $274.00 ; 100 μg $411.00

sp-pme101802 cntn2 sp1

ECD Proteins

Human CNTN2 Protein, His Tag

SKU:  PME101802     Target:  CNTN2

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101677b bcma sp1

ECD Proteins

Biotinylated Human BCMA Protein, hFc Avi Tag

SKU:  PME101677B     Target:  BCMA

Price:10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-pme m100125 cxcr2 sp1

ECD Proteins

Mouse CXCR2 Protein, hFc Tag

SKU:  PME-M100125     Target:  CXCR2

Price:10μg $72.00; 50μg $272.00; 100μg $409.00

sp-pme c100088 cxcr2 sp1

ECD Proteins

Cynomolgus CXCR2(1-63) Protein, hFc Tag

SKU:  PME-C100088     Target:  CXCR2

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme c100087 cd94 sp1

ECD Proteins

Cynomolgus CD94 Protein, hFc Tag

SKU:  PME-C100087     Target:  CD94

Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00

sp-pme c100086 nkg2a sp1

ECD Proteins

Cynomolgus NKG2A Protein, hFc Tag

SKU:  PME-C100086     Target:  NKG2A

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101801 agtr2 sp1

ECD Proteins

Human AGTR2 Protein, hFc Tag

SKU:  PME101801     Target:  AGTR2

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101800 adrb3 sp1

ECD Proteins

Human ADRB3 Protein, hFc Tag

SKU:  PME101800     Target:  ADRB3

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101799 adra1a sp1

ECD Proteins

Human ADRA1A Protein, hFc Tag

SKU:  PME101799     Target:  ADRA1A

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101798 ephb4 sp1

ECD Proteins

Human EPHB4 Protein, His Tag

SKU:  PME101798     Target:  EPHB4

Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00

sp-pme101797 mc3r sp1

ECD Proteins

Human MC3R Protein, hFc Tag

SKU:  PME101797     Target:  MC3R

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101796 mc2r sp1

ECD Proteins

Human MC2R Protein, hFc Tag

SKU:  PME101796     Target:  MC2R

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101795 fcgrt sp1

ECD Proteins

Human FCGRT Protein, His Tag

SKU:  PME101795     Target:  FCGRT

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101794 vegfb sp1

ECD Proteins

Human VEGFB Protein, hFc Tag

SKU:  PME101794     Target:  VEGFB

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101791 fgf21 sp1

ECD Proteins

Human FGF21 Protein, His Tag

SKU:  PME101791     Target:  FGF21

Price:10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00

sp-pme101790 cd19 sp1

ECD Proteins

Human CD19 Protein, His Tag

SKU:  PME101790     Target:  CD19

Price:10μg $85.00; 50μg $310.00 ; 100 μg $460.00

sp-pme101789 pd 1 sp1

ECD Proteins

Human PD-1(25-145) Protein, hFc Tag

SKU:  PME101789     Target:  PD-1

Price:10μg $96.00; 50μg $370.00 ; 100 μg $555.00

sp-pme101788 htr7 sp1

ECD Proteins

Human HTR7 Protein, hFc Tag

SKU:  PME101788     Target:  HTR7

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101787 kiss1r sp1

ECD Proteins

Human KISS1R Protein, hFc Tag

SKU:  PME101787     Target:  KISS1R

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101786 lilrb1 sp1

ECD Proteins

Human LILRB1 Protein, His Tag

SKU:  PME101786     Target:  LILRB1

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101785 lilra6 sp1

ECD Proteins

Human LILRA6 Protein, His Tag

SKU:  PME101785     Target:  LILRA6

Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00

sp-pme101784 tacr2 sp1

ECD Proteins

Human TACR2 Protein, hFc Tag

SKU:  PME101784     Target:  TACR2

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101783 tacr2 sp1

ECD Proteins

Human TACR2 Protein, mFc Tag

SKU:  PME101783     Target:  TACR2

Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

sp-pme101782 lgals4 sp1

ECD Proteins

Human LGALS4 Protein, His Tag

SKU:  PME101782     Target:  LGALS4

Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00

sp-pme101781 fgf9 sp1

ECD Proteins

Human FGF9 Protein, His Tag

SKU:  PME101781     Target:  FGF9

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00

sp-pme101780 lilra1 sp1

ECD Proteins

Human LILRA1 Protein, His Tag

SKU:  PME101780     Target:  LILRA1

Price:10μg $100.00 ; 50μg $358.00 ; 100μg $528.00