Extracellular Domain Protein (ECD)

DIMA BIOTECH offers over 1000 ECD proteins covering more than 600 single pass membrane protein targets. All the proteins were made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target proteins. We also implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing tests, thermal stability tests, etc. 

Applications:

  • Immunogens for antibody drug development
  • Reagents used for CAR-T positive cell monitoring
  • Reagents for antibody screening and functional testing
  • Reagents for antibody affinity measurement
View All ECD Proteins

Hot Duggable Targets

Immune checkpoints are a class of proteins that regulate tumor immune microenvironment.

They can be classified into two categories, costimulatory immune checkpoints, such as OX40, GITR, ICOS, etc.; and co-suppressive immune checkpoints, such as PD1, CTLA-4, etc.

Right now there are a number of FDA approved drugs on co-suppressive targets, such as Yervoy, anti-CTLA-4 monoclonal antibody, Keytruda, anti-PD-1 monoclonal antibody and Tecentriq, anti-PD-L1 monoclonal antibody.

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DIMA Biotechnology LTD provide a full spectrum of functional proteins of new CAR T-cell targets.

All the proteins were made by using HEK293 mammalian cell secretion expression system and we implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing Tests, thermal stability tests, etc.

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In recent years, the biopharmaceutical market is growing rapidly.

Compared with small molecule drugs, antibody drugs exhibit higher specificity and selectivity.

Therefore, it showed tremendous progresses in the treatment of hematological cancers and autoimmune diseases.

Due to complex tumor immune microenvironment, the development of therapeutic antibody drugs for solid tumor is more challenging.

ECD Proteins

sp-PME M100105 CD98 Fig.1 SDS PAGE 1

ECD Proteins

Mouse CD98 Protein, His Tag

SKU:  PME-M100105     Target:  CD98

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME M100104 TFRC Fig.1 SDS PAGE 1

ECD Proteins

Mouse TFRC Protein, His Tag

SKU:  PME-M100104     Target:  TFRC

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME M100103 PSMA Fig.1 SDS PAGE 1

ECD Proteins

Mouse PSMA Protein, His Tag

SKU:  PME-M100103     Target:  PSMA

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101495 FCRL5 Fig.1 SDS PAGE 1

ECD Proteins

Human FCRL5(745-847)Protein, mFc Tag

SKU:  PME101495     Target:  FCRL5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101494 FCRL5 Fig.1 SDS PAGE 1

ECD Proteins

Human FCRL5(745-850)Protein, hFc Tag

SKU:  PME101494     Target:  FCRL5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101493 FCRL5 Fig.1 SDS PAGE 1

ECD Proteins

Human FCRL5(745-847)Protein, hFc Tag

SKU:  PME101493     Target:  FCRL5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101425 MC4R Fig.1 SDS PAGE 1

ECD Proteins

Human MC4R Protein, hFc Tag

SKU:  PME101425     Target:  MC4R

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101424 XCR1 Fig.1 SDS PAGE 1

ECD Proteins

Human XCR1 Protein, hFc Tag

SKU:  PME101424     Target:  XCR1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101423 BAMBI Fig.1 SDS PAGE 1

ECD Proteins

Human BAMBI Protein, hFc Tag

SKU:  PME101423     Target:  BAMBI

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101422 CCL3 Fig.1 SDS PAGE 1

ECD Proteins

Human CCL3 Protein, hFc Tag

SKU:  PME101422     Target:  CCL3

Price: 10μg $120.00 ; 50μg $450.00 ; 100 μg $660.00

sp-PME101421 CCL5 Fig.1 SDS PAGE 1

ECD Proteins

Human CCL5 Protein, hFc Tag

SKU:  PME101421     Target:  CCL5

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101420 IFNA2 Fig.1 SDS PAGE 1

ECD Proteins

Human IFNA2 Protein, hFc Tag

SKU:  PME101420     Target:  IFNA2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101419 CRCP Fig.1 SDS PAGE 1

ECD Proteins

Human CRCP Protein, hFc Tag

SKU:  PME101419     Target:  CRCP

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101418 ADAM17 Fig.1 SDS PAGE 1

ECD Proteins

Human ADAM17(581-642) Protein, mFc Tag

SKU:  PME101418     Target:  ADAM17

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101417 LEP Fig.1 SDS PAGE 1

ECD Proteins

Human LEP Protein, hFc Tag

SKU:  PME101417     Target:  LEP

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101416 ADIPOQ Fig.1 SDS PAGE 1

ECD Proteins

Human ADIPOQ Protein, hFc Tag

SKU:  PME101416     Target:  ADIPOQ

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101415 APOA2 Fig.1 SDS PAGE 1

ECD Proteins

Human APOA2 Protein, hFc Tag

SKU:  PME101415     Target:  APOA2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101414 GAL Fig.1 SDS PAGE 1

ECD Proteins

Human GAL Protein, hFc Tag

SKU:  PME101414     Target:  GAL

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101413 ADGRD1 Fig.1 SDS PAGE 1

ECD Proteins

Human ADGRD1 Protein, His Tag

SKU:  PME101413     Target:  ADGRD1

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101412 HER3 Fig.1 SDS PAGE 1

ECD Proteins

Human HER3(544-643) Protein, mFc Tag

SKU:  PME101412     Target:  HER3

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101411 HER3 Fig.1 SDS PAGE 1

ECD Proteins

Human HER3(544-643) Protein, hFc Tag

SKU:  PME101411     Target:  HER3

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101410 OR2H1 Fig.1 SDS PAGE 1

ECD Proteins

Human OR2H1 Protein, hFc Tag

SKU:  PME101410     Target:  OR2H1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101408 FGFR2IIIb Fig.1 SDS PAGE 1

ECD Proteins

Human FGFR2b Protein, His Tag

SKU:  PME101408     Target:  FGFR2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101407 KLK1 Fig.1 SDS PAGE 1

ECD Proteins

Human KLK1 Protein, His Tag

SKU:  PME101407     Target:  KLK1

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101406 IL31RA Fig.1 SDS PAGE 1

ECD Proteins

Human IL31RA Protein, His Tag

SKU:  PME101406     Target:  IL31RA

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101405 MET Fig.1 SDS PAGE 1

ECD Proteins

Human MET Protein, His Tag

SKU:  PME101405     Target:  MET

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101403 GLP2R Fig.1 SDS PAGE 1

ECD Proteins

Human GLP2R Protein, His Tag

SKU:  PME101403     Target:  GLP2R

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101402 TIM4 Fig.1 SDS PAGE 1

ECD Proteins

Human TIM4 Protein, His Tag

SKU:  PME101402     Target:  TIM4

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101401 ADGRE5 Fig.1 SDS PAGE 1

ECD Proteins

Human ADGRE5 Protein, His Tag

SKU:  PME101401     Target:  ADGRE5

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101396 CFI Fig.1 SDS PAGE 1

ECD Proteins

Human CFI Protein, His Tag

SKU:  PME101396     Target:  CFI

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101395 PSAP Fig.1 SDS PAGE 1

ECD Proteins

Human SAP Protein, His Tag

SKU:  PME101395     Target:  SAP

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101394 C1S Fig.1 SDS PAGE 1

ECD Proteins

Human C1S Protein, His Tag

SKU:  PME101394     Target:  C1S

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00