Extracellular Domain Protein (ECD)

DIMA BIOTECH offers over 1000 ECD proteins covering more than 600 single pass membrane protein targets. All the proteins were made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target proteins. We also implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing tests, thermal stability tests, etc. 

Applications:

  • Immunogens for antibody drug development
  • Reagents used for CAR-T positive cell monitoring
  • Reagents for antibody screening and functional testing
  • Reagents for antibody affinity measurement
View All ECD Proteins

Hot Duggable Targets

Immune checkpoints are a class of proteins that regulate tumor immune microenvironment.

They can be classified into two categories, costimulatory immune checkpoints, such as OX40, GITR, ICOS, etc.; and co-suppressive immune checkpoints, such as PD1, CTLA-4, etc.

Right now there are a number of FDA approved drugs on co-suppressive targets, such as Yervoy, anti-CTLA-4 monoclonal antibody, Keytruda, anti-PD-1 monoclonal antibody and Tecentriq, anti-PD-L1 monoclonal antibody.

pages-416107bc534d939 1

DIMA Biotechnology LTD provide a full spectrum of functional proteins of new CAR T-cell targets.

All the proteins were made by using HEK293 mammalian cell secretion expression system and we implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing Tests, thermal stability tests, etc.

pages-cvsdvdfffffb 1

In recent years, the biopharmaceutical market is growing rapidly.

Compared with small molecule drugs, antibody drugs exhibit higher specificity and selectivity.

Therefore, it showed tremendous progresses in the treatment of hematological cancers and autoimmune diseases.

Due to complex tumor immune microenvironment, the development of therapeutic antibody drugs for solid tumor is more challenging.

ECD Proteins

sp-PME101328 MXRA8 Fig.1 SDS PAGE 1

ECD Proteins

Human MXRA8 Protein, His Tag

SKU:  PME101328     Target:  MXRA8

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101327 LILRB5 Fig.1 SDS PAGE 1

ECD Proteins

Human LILRB5 Protein, His Tag

SKU:  PME101327     Target:  LILRB5

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101326 LILRA2 Fig.1 SDS PAGE 1

ECD Proteins

Human LILRA2 Protein, His Tag

SKU:  PME101326     Target:  LILRA2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101325 IL13RA2 Fig.1 SDS PAGE 1

ECD Proteins

Human IL13RA2 Protein, hFc Tag

SKU:  PME101325     Target:  IL13RA2

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101324 VWF Fig.1 SDS PAGE 1

ECD Proteins

Human VWF(1596-1668) Protein, hFc Tag

SKU:  PME101324     Target:  VWF

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101323 GPR65 Fig.1 SDS PAGE 1

ECD Proteins

Human GPR65 Protein, hFc Tag

SKU:  PME101323     Target:  GPR65

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101322 CD79A Fig.1 SDS PAGE 1

ECD Proteins

Human CD79A Protein, hFc Tag

SKU:  PME101322     Target:  CD79A

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101321 EGFRVIII Fig.1 SDS PAGE 1

ECD Proteins

Human EGFRVIII Protein, His Tag

SKU:  PME101321     Target:  EGFRVIII

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101320 ENPP2 Fig.1 SDS PAGE 1

ECD Proteins

Human ENPP2 Protein, His Tag

SKU:  PME101320     Target:  ENPP2

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101319 CSPG5 Fig.1 SDS PAGE 1

ECD Proteins

Human CSPG5 Protein, His Tag

SKU:  PME101319     Target:  CSPG5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101318 IL1RL2 Fig.1 SDS PAGE 1

ECD Proteins

Human IL1RL2 Protein, His Tag

SKU:  PME101318     Target:  IL1RL2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101317 SEMA7A Fig.1 SDS PAGE 1

ECD Proteins

Human SEMA7A Protein, His Tag

SKU:  PME101317     Target:  SEMA7A

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101316 PLAT Fig.1 SDS PAGE 1

ECD Proteins

Human PLAT Protein, His Tag

SKU:  PME101316     Target:  PLAT

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101315 CCL11 Fig.1 SDS PAGE 1

ECD Proteins

Human CCL11 Protein, hFc Tag

SKU:  PME101315     Target:  CCL11

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101314 CFD Fig.1 SDS PAGE 1

ECD Proteins

Human CFD Protein, hFc Tag

SKU:  PME101314     Target:  CFD

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101313 CLEC5A Fig.1 SDS PAGE 1

ECD Proteins

Human CLEC5A Protein, hFc Tag

SKU:  PME101313     Target:  CLEC5A

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101312 LOX 1 Fig.1 SDS PAGE 1

ECD Proteins

Human LOX-1 Protein, hFc Tag

SKU:  PME101312     Target:  LOX-1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101311 LILRB4 Fig.1 SDS PAGE 1

ECD Proteins

Human LILRB4 Protein, hFc Tag

SKU:  PME101311     Target:  LILRB4

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101310 CLEC4C Fig.1 SDS PAGE 1

ECD Proteins

Human CLEC4C Protein, His Tag

SKU:  PME101310     Target:  CLEC4C

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101308 IGSF11 Fig.1 SDS PAGE 1

ECD Proteins

Human IGSF11 Protein, hFc Tag

SKU:  PME101308     Target:  IGSF11

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101307 IL4 Fig.1 SDS PAGE 1

ECD Proteins

Human IL4 Protein, mFc Tag

SKU:  PME101307     Target:  IL4

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101306 CD98 Fig.1 SDS PAGE 1

ECD Proteins

Human CD98 Protein, His Tag

SKU:  PME101306     Target:  CD98

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101304 PAI1 Fig.1 SDS PAGE 1

ECD Proteins

Human PAI1 Protein, His Tag

SKU:  PME101304     Target:  PAI1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101303 MELTF Fig.1 SDS PAGE 1

ECD Proteins

Human MELTF Protein, His Tag

SKU:  PME101303     Target:  MELTF

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101292 GPR64 Fig.1 SDS PAGE 1

ECD Proteins

Human GPR64 Protein, His Tag

SKU:  PME101292     Target:  GPR64

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME100319 KIR2DL3 Fig.1 SDS PAGE 1

ECD Proteins

Human KIR2DL3 Protein, His Tag

SKU:  PME100319     Target:  KIR2DL3

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME100213 CRLF2 Fig.1 SDS PAGE 1

ECD Proteins

Human CRLF2 Protein, His Tag

SKU:  PME100213     Target:  CRLF2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

elisa-PME30021 C687 P08476 ELISA 0

ECD Proteins

Human/Mouse/Rat Activin A Protein

SKU:  PME30021     Target:  Activin

Price: 50 μg $503.00

sp-PME C100016 SELPLG Fig.1 SDS PAGE 1

ECD Proteins

Cynomolgus SELPLG Protein, His Tag

SKU:  PME-C100016     Target:  SELPLG

Price:10μg $95.00; 50μg $330.00; 100μg $500.00

sp-PME C100015 IL18BP Fig.1 SDS PAGE 1

ECD Proteins

Cynomolgus IL18BP Protein, His Tag

SKU:  PME-C100015     Target:  IL18BP

Price: 10μg $100.00 ; 50μg $375.00 ; 100 μg $550.00

sp-PME C100014 CD93 Fig.1 SDS PAGE 1

ECD Proteins

Cynomolgus CD93 Protein, His Tag

SKU:  PME-C100014     Target:  CD93

Price:10μg $95.00; 50μg $330.00; 100μg $500.00

sp-PME C100013 CLEC4C Fig.1 SDS PAGE 1

ECD Proteins

Cynomolgus CLEC4C Protein, His Tag

SKU:  PME-C100013     Target:  CLEC4C

Price: 10μg $100.00 ; 50μg $375.00 ; 100 μg $550.00