Extracellular Domain Protein (ECD)

DIMA BIOTECH offers over 1000 ECD proteins covering more than 600 single pass membrane protein targets. All the proteins were made using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target proteins. We also implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing tests, thermal stability tests, etc. 

Applications:

  • Immunogens for antibody drug development
  • Reagents used for CAR-T positive cell monitoring
  • Reagents for antibody screening and functional testing
  • Reagents for antibody affinity measurement
View All ECD Proteins

Hot Duggable Targets

Immune checkpoints are a class of proteins that regulate tumor immune microenvironment.

They can be classified into two categories, costimulatory immune checkpoints, such as OX40, GITR, ICOS, etc.; and co-suppressive immune checkpoints, such as PD1, CTLA-4, etc.

Right now there are a number of FDA approved drugs on co-suppressive targets, such as Yervoy, anti-CTLA-4 monoclonal antibody, Keytruda, anti-PD-1 monoclonal antibody and Tecentriq, anti-PD-L1 monoclonal antibody.

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DIMA Biotechnology LTD provide a full spectrum of functional proteins of new CAR T-cell targets.

All the proteins were made by using HEK293 mammalian cell secretion expression system and we implemented a strict quality control process, including purity testing, antibody-drug interaction verification, freezing and thawing Tests, thermal stability tests, etc.

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In recent years, the biopharmaceutical market is growing rapidly.

Compared with small molecule drugs, antibody drugs exhibit higher specificity and selectivity.

Therefore, it showed tremendous progresses in the treatment of hematological cancers and autoimmune diseases.

Due to complex tumor immune microenvironment, the development of therapeutic antibody drugs for solid tumor is more challenging.

ECD Proteins

sp-PME C100012 ADAM9 Fig.1 SDS PAGE 1

ECD Proteins

Cynomolgus ADAM9 Protein, His Tag

SKU:  PME-C100012     Target:  ADAM9

Price:10μg $95.00; 50μg $330.00; 100μg $500.00

sp-PME101302 GPR81 Fig.1 SDS PAGE 1

ECD Proteins

Human GPR81 Protein, hFc Tag

SKU:  PME101302     Target:  GPR81

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101301 p16 Fig.1 SDS PAGE 1

ECD Proteins

Human p16(110-139) Protein, hFc Tag

SKU:  PME101301     Target:  p16

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101300 p16 Fig.1 SDS PAGE 1

ECD Proteins

Human p16(77-106) Protein, hFc Tag

SKU:  PME101300     Target:  p16

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101299 p16 Fig.1 SDS PAGE 1

ECD Proteins

Human p16(44-72) Protein, hFc Tag

SKU:  PME101299     Target:  p16

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101298 p16 Fig.1 SDS PAGE 1

ECD Proteins

Human p16(11-40) Protein, hFc Tag

SKU:  PME101298     Target:  p16

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101297 IBSP Fig.1 SDS PAGE 1

ECD Proteins

Human IBSP Protein, His Tag

SKU:  PME101297     Target:  IBSP

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101296 IL4 Fig.1 SDS PAGE 1

ECD Proteins

Human IL4 Protein, His Tag

SKU:  PME101296     Target:  IL4

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101295 ARTN Fig.1 SDS PAGE 1

ECD Proteins

Human ARTN Protein, hFc Tag

SKU:  PME101295     Target:  ARTN

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101294 S100A9 Fig.1 SDS PAGE 1

ECD Proteins

Human S100A9 Protein, hFc Tag

SKU:  PME101294     Target:  S100A9

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101291 FSTL1 Fig.1 SDS PAGE 1

ECD Proteins

Human FSTL1 Protein, His Tag

SKU:  PME101291     Target:  FSTL1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101289 CALCA Fig.1 SDS PAGE 1

ECD Proteins

Human CALCA(26-141) Protein, hFc Tag

SKU:  PME101289     Target:  CALCA

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101288 CXCL5 Fig.1 SDS PAGE 1

ECD Proteins

Human CXCL5 Protein, hFc Tag

SKU:  PME101288     Target:  CXCL5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101287 DSG2 Fig.1 SDS PAGE 1

ECD Proteins

Human DSG2(24-609) Protein, His Tag

SKU:  PME101287     Target:  DSG2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101286 DSG2 Fig.1 SDS PAGE 1

ECD Proteins

Human DSG2(50-609) Protein, His Tag

SKU:  PME101286     Target:  DSG2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101285 FGF19 Fig.1 SDS PAGE 1

ECD Proteins

Human FGF19 Protein, His Tag

SKU:  PME101285     Target:  FGF19

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101284 PTGFRN Fig.1 SDS PAGE 1

ECD Proteins

Human PTGFRN Protein, His Tag

SKU:  PME101284     Target:  PTGFRN

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101283 CD300LF Fig.1 SDS PAGE 1

ECD Proteins

Human CD300LF Protein, hFc Tag

SKU:  PME101283     Target:  CD300LF

Price: 10μg $79.00; 50μg $281.00 ; 100μg $422.00

sp-PME101282 CHRM2 Fig.1 SDS PAGE 1

ECD Proteins

Human CHRM2 Protein, hFc Tag

SKU:  PME101282     Target:  CHRM2

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101281 PF4V1 Fig.1 SDS PAGE 1

ECD Proteins

Human PF4V1 Protein, hFc Tag

SKU:  PME101281     Target:  PF4V1

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-pme100730 cd3d cd3e sp1

ECD Proteins

Human CD3D Protein, His Tag and Human CD3E Protein, hFc Tag

SKU:  PME100730     Target:  CD3D; CD3E

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101305 CGRP Fig.1 SDS PAGE 1

ECD Proteins

Human CGRP Protein, hFc Tag

SKU:  PME101305     Target:  CGRP

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101293 CDH19 Fig.1 SDS PAGE 1

ECD Proteins

Human CDH19 Protein, His Tag

SKU:  PME101293     Target:  CDH19

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101290 FCGR3B Fig.1 SDS PAGE 1

ECD Proteins

Human FCGR3B Protein, His Tag

SKU:  PME101290     Target:  FCGR3B

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101280 ECSCR Fig.1 SDS PAGE 1

ECD Proteins

Human ECSCR Protein, hFc Tag

SKU:  PME101280     Target:  ECSCR

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101279 TAFA5 Fig.1 SDS PAGE 1

ECD Proteins

Human TAFA5 Protein, hFc Tag

SKU:  PME101279     Target:  TAFA5

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101278 FCGR3B Fig.1 SDS PAGE 1

ECD Proteins

Human FCGR3B Protein, hFc Tag

SKU:  PME101278     Target:  FCGR3B

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101277 GPR75 Fig.1 SDS PAGE 1

ECD Proteins

Human GPR75 Protein, mFc Tag

SKU:  PME101277     Target:  GPR75

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101276 CPM Fig.1 SDS PAGE 1

ECD Proteins

Human CPM Protein, His Tag

SKU:  PME101276     Target:  CPM

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00

sp-PME101275 MANSC1 Fig.1 SDS PAGE 1

ECD Proteins

Human MANSC1 Protein, His Tag

SKU:  PME101275     Target:  MANSC1

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101274 PILRA Fig.1 SDS PAGE 1

ECD Proteins

Human PILRA Protein, hFc Tag

SKU:  PME101274     Target:  PILRA

Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00

sp-PME101273 GPR20 Fig.1 SDS PAGE 1

ECD Proteins

Human GPR20 Protein, hFc Tag

SKU:  PME101273     Target:  GPR20

Price: 10μg $70.00; 50μg $244.00 ; 100μg $367.00